Thank you for sending your Spine project via email!
1.I can't flip it as ik won't flip using ctrl bone even all iks' are child to this bone.
Your skeleton has a bone (spine2) that its inheritance of Rotation is disabled, it is preventing the flip. The reason why inversion is not possible when rotation inheritance is disabled has been explained in the past in this thread, so please see here for more details:
Inherit Rotation still affecting negative scale in parent.
A possible solution would be: Instead of making the spine2 bone a direct child of spine1, create a holder bone and then create a transform constraint to it so that spine2 follows spine1 while maintaining the rotation angle of spine2. Please see the Spine project sent to you via email for the details.
2.I can't activate auto key ON as it won't appear on the screen.
Note that the Auto Key button can only be toggled on and off in animate mode. If you are still not seeing the Auto Key button in animate mode, could you please send us a screenshot of it?
