Hello, it was a bit hard to understand, but I'll try my best to answer every part.

TeT escribió

When I switching off the mesh in one skin, the switching off keys are inverted in another skins and color animation is disappearing.

I think what you're experiencing is that you're either not using skin placeholders to store the images inside (as one would normally do when using skins), or you are using skin placeholders, but too many and they should be merged together if when you change skin one deactivates another. To both the solution is to create a skin placeholder and store both images that should be active in the same animation under the sane skin placeholder.

TeT escribió

I put only bones in skins

You should put bones in skins only if these bones are not needed by other skins, otherwise this doesn't help.

TeT escribió

All meshes not duplicated, cuz all sprites different. All meshes have there own bones.

Are you sure some of these meshes can't be put in the same slot as the others? Perhaps your characters really differ so extremely that they need multiple bones, but a good skeleton structure will try to reuse as many bones in common as possible. If you want to share some images of your skeleton I could try to help, but it's up to you.