Hello! If you uncheck bones visibility or layer visibility, you can focus on only the selected elements.
Tools - Spine User Guide: Options
Furthermore, right-clicking a bone's visibility will hide it and all of its children, as well as hide slots (which only affects the editor, not runtime).
This greatly speeds up hiding chunks of elements obscuring your view and makes restoring them also quite easy, just right-click the parent bone again.
You can also store selections of several bones or other elements obscuring your view, and recall them to quickly activate/deactivate them by pressing CTRL
plus a number from 0 to 9, then recalling the selection by pressing the corresponding number.