We have an issue with a bunch of different spine files that have left of very puzzled. Graphics disappear on iOS 10 in Safari. Sometimes it reappears, sometimes not. Sometimes it disappears for an instant, sometimes for a longer period of time. We have detected the issue in iOS 10.1 and 10.2. It is not present in 10.3 or 11. We have not yet found an iOS 10.0 device to test on, but on iOS 8 it is not happening. We have narrowed it down to somewhere in the spine typescript runtime since it is happening in various examples on Spine: Demos. For example in the "Transitions and layering" example.
In the video, the animation speed is 0%, however it is also happening with different animation speeds. Note that it only occurs in the example that uses mixing.
We have observed the bug on both canvas and webgl while using our own rendering implementation.